Breast – Breast Cancer

Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer.

In women, breast cancer is the second most common cancer, followed by skin cancer. Mammograms can detect breast cancer early, perhaps before it spreads.

Tag Archive for: Breast

Chemotherapy and Oncothermia association

Lower and less toxic doses of chemotherapy by combining it with Oncothermia and complementary treatments.

Modelo EHY-2000 de Oncothermia

Professor Dr. med. Alexander Herzog, Chief-physician, Fachklinik Dr. Herzog, Germany has published a recent clinical study in the Oncothermia journal. He also presented it at the 35th ICHS, Guangzhou, China, 2017. The study explains the results in the use of lower and less toxic doses of chemotherapy when combined with hyperthermia and complementary treatments.

Electro-hyperthermia (Oncothermia) is an important tool for improving the efficacy of chemotherapy and radiation in cancer.

Numerous studies have been published on Oncothermia treatment in cell cultures, in animal experiments, but also in patients. Furthermore, these studies include randomised studies, phase 2 studies, but also many successful case reports that provide evidence for the benefit of Oncothermia.


Oncothermy means heating the cancerous tissue up to 42°C (107.6°F). In several experiments, it has been shown that chemotherapy works more efficiently if the temperature of the cancer tissue is increased. There can be a linear or even exponential increase in the activity of cytostatic drugs.

The Oncotherm device with 13.56 MHz and energies up to 150 watts was used. The local treatment takes 1 hour for each session. In addition, such treatment can be repeated frequently (the interval between 2 treatments should be at least 48 hours to avoid thermal tolerance).

Chemotherapy is administered simultaneously with a local Oncothermia session.

Results for a selection of different cancers:

♦ ENT-Cancers:

The standard chemotherapy in these cases would be a rather toxic 5-day programme of cisplatin together with 5-FU as a continuous infusion. Together with oncothermia, a 4-day programme would be sufficient.

♦ Non-small cell lung cancer:

The dosing regimen would follow platinum-based chemotherapy, but the doses of Carboplatin and Gemcitabine or Vinorelbine could be reduced by approximately 20%, if applied together with Oncothermia.

♦ Colorectal cancer:

Chemotherapy protocols in colorectal cancer are mainly the FOLFOX protocol and the Folfiri protocol, which can be combined with Bevacizumab or Cetuximab antibodies. Together with Oncothermia, the dose of Oxaliplatin would be kept at the standard level. Irinotecan could be reduced. 5-FU administered as a chronomodulated treatment at night with 50% of the dose between 2 a.m. and 6 a.m. could also be significantly reduced. In addition, Capecitabine can be used together with Oncothermia at a reduced dose.

♦ Ovarian and cervical cancers:

In ovarian and cervical cancer, the standard chemotherapy is Carboplatin and the neurotoxic drug Paclitaxel. Together with Oncothermia, Carboplatin could be combined with a less toxic dose of Cyclophosphamide, which is a drug with potentiation of its activity under hyperthermic conditions.

♦ Breast cancer:

In one study, it has been shown that 70-80% of breast cancer patients respond to a treatment programme with local oncothermia together with moderate doses of chemotherapy.

Reduces toxicity

In conjunction with oncothermia, it is possible to use chemotherapy in more moderate doses. This reduces toxicity. Above all, it helps patients in particular in the palliative situation to preserve quality of life. It also allows for more regular treatments and for a longer period of time which is possibly very important to improve survival times.


Herzog A. (2018): Lower and less toxic doses of chemotherapy by combining it with hyperthermia and complementary treatments; Oncothermia Journal 22:46-56

Breast Cancer treated with Chemotherapy and Oncothermia

The following is the clinical case of a 51 year old female patient. The diagnosis is infiltrating ductal carcinoma of the left breast. She was treated with chemotherapy, combined with oncothermia.


She presented in May 2016 with breast cancer, infiltrating ductal carcinoma of the left breast. Consequently, the MRI shows multiple and extensive irregular confluent foci. In addition, the cancer forms a mass measuring 79 mm x 52 mm x 58 mm extending to the nipple-areola complex with infiltration of the dermis.


In June 2016 she started chemotherapy with Paclitaxel and Trastuzumab. Subsequently, in August 2016, oncothermia treatment was started, with 60-minute sessions.


In October 2016 a breast MRI is performed for control, after the administration of 9 sessions of chemotherapy and 6 sessions of 60-minute oncothermia.

The result of the MRI shows disappearance of the tumour mass indicating a complete response to treatment.

Consequently, the patient refuses surgical treatment as there is no tumour mass and continues with radiological controls. In October 2018 the patient has shown no signs of recurrence.

If you wish, you can find more information about breast cancer treated with Oncothermia on our website at this link.