Oncothermia increases the susceptibility of tumours to radiotherapy, as the former has a radiosensitising potential. The addition of oncothermia improves relevant clinical endpoints such as response rate, local control and overall survival. It increases oxygenation, reducing hypoxia (lack of cellular oxygen) and amplifies the cytotoxic effect of radiation. Oncothermia also repairs cell damage caused by radiation. Moreover, it does not present additional toxicities and may be a promising alternative for elderly and/or frail patients.